HR 358 — A Resolution recognizing November 1, 2025, as "Tylenol Day" in Pennsylvania.

PRINTER'S NO.    2527

                  THE GENERAL ASSEMBLY OF PENNSYLVANIA



           HOUSE RESOLUTION
              No. 358
                                              Session of
                                                2025

     INTRODUCED BY SCOTT, DALEY, SANCHEZ, HOWARD, KENYATTA AND
        GUENST, OCTOBER 24, 2025

     REFERRED TO COMMITTEE ON HEALTH, OCTOBER 27, 2025


                               A RESOLUTION
 1   Recognizing November 1, 2025, as "Tylenol Day" in Pennsylvania.
 2      WHEREAS, In 1884, two German physicians prescribed
 3   naphthalene to a patient they were treating for worms and a
 4   fever; and
 5      WHEREAS, The naphthalene did not relieve the patient's worms,
 6   but it did reduce the patient's fever, an effect that was not
 7   previously known; and
 8      WHEREAS, The physicians learned that the pharmacy had made a
 9   mistake and provided acetanilide, a compound isolated from coal
10   tar; and
11      WHEREAS, The physicians worked with a pharmaceutical firm to
12   investigate the effects of acetanilide and confirmed that it
13   reduced fever; and
14      WHEREAS, After acetanilide was marketed as Antifebrin, users
15   reported bluish skin after taking it; and
16      WHEREAS, The cause of the bluish skin was identified as
17   methemoglobinemia, a condition in which the oxygen transported
 1   by hemoglobin is impaired; and
 2      WHEREAS, These findings led researchers to seek safer
 3   alternatives by altering the molecular structure of compounds to
 4   eliminate side effects; and
 5      WHEREAS, In 1887, a German company known as Bayer modified
 6   acetanilide to produce phenacetin, which did not cause
 7   methemoglobinemia; and
 8      WHEREAS, Later in 1887, a physician and a chemist worked
 9   together to find another derivative of acetanilide, now known as
10   acetaminophen; and
11      WHEREAS, The founders of acetaminophen recommended an
12   extensive investigation into the medication before it became
13   available to the public; and
14      WHEREAS, The effectiveness and safety of acetaminophen as a
15   fever and pain reliever were not confirmed until 1949, based on
16   modern research techniques and clinical use in England; and
17      WHEREAS, Because phenacetin was linked to kidney problems and
18   aspirin to stomach problems, acetaminophen was promoted as the
19   safer medication; and
20      WHEREAS, In the late 1940s, McNeil Laboratories, a
21   Philadelphia family-owned business, began studying the safety
22   and efficacy of acetaminophen in hopes of marketing it for a
23   future product; and
24      WHEREAS, McNeil Laboratories began as a family-run pharmacy
25   and later expanded into the manufacturing of prescription
26   medicines; and
27      WHEREAS, In 1955, McNeil Laboratories introduced Tylenol
28   Elixir for Children after receiving approval by the United
29   States Food and Drug Administration (FDA); and
30      WHEREAS, Tylenol Elixir for Children was the first single-

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 1   ingredient acetaminophen product on the market and was available
 2   only by prescription; and
 3      WHEREAS, In 1959, Johnson & Johnson acquired McNeil
 4   Laboratories; and
 5      WHEREAS, In 1959, Tylenol was approved for sale without a
 6   prescription, leading to its availability over the counter the
 7   following year; and
 8      WHEREAS, Tylenol has become the best-known product of the
 9   more than 600 products on the market that contain the active
10   ingredient acetaminophen; and
11      WHEREAS, Tylenol has more than two dozen products in various
12   forms, including liquids, dissolvable powders, chewable tablets,
13   caplets and capsules; and
14      WHEREAS, Each Tylenol product is formulated for different
15   symptoms, age groups and delivery methods; and
16      WHEREAS, Tylenol offers products for pain and fever relief,
17   as well as for arthritis, cold and flu symptoms, sinus relief
18   and sleep; and
19      WHEREAS, It is estimated that nearly 25% of adults in the
20   United States use a medication containing acetaminophen each
21   week; and
22      WHEREAS, Tylenol is the number one doctor-recommended pain
23   reliever brand; and
24      WHEREAS, The year 2025 commemorates the 70th anniversary of
25   Tylenol receiving FDA approval and being introduced by McNeil
26   Laboratories; therefore be it
27      RESOLVED, That the House of Representatives recognize
28   November 1, 2025, as "Tylenol Day" in Pennsylvania.




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